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Quarterly Journal of Experimental Physiology 20.4 pp 305-311
© The Physiological Society 1930
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STUDIES IN BLOOD DIASTASE. FACTORS WHICH CAUSE VARIATIONS IN THE AMOUNT OF DIASTASE IN THE BLOOD

Charles Reid 1 and B. Narayana 1

1 Department of Physiology, Prince of Wales Medical College, Patna

1. The blood diastase decreases after meals, injections of glucose, glycogen, and insulin, while anæsthetics and injections of starch cause a slight increase.

2. Since pancreatectomy causes little or no change in the amount of circulating diastase, the pancreas is not the main source of blood diastase. Ligature of the pancreatic duct does not result in any striking change in the diastase content of the blood in the course of one to two weeks.

3. Since definite variations can be induced in the blood diastase by injections of insulin, glycogen, etc., it appears likely that the circulating diastase is not entirely a waste product on its way to excretion.

4. Evidence is adduced that variations in blood diastase are probably due to its being taken up or given out by the liver cells, etc., according to the requirements of the body with respect to the glycogen glucose, probably in association with insulin.

Submitted on August 15, 1930






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Copyright © 1930 by the The Physiological Society.