STUDIES ON THE ARNETH COUNT.—XVII. THE EFFECT OF ALTERATIONS OF THE SERUM-CALCIUM LEVEL ON THE COUNT

¹ Department of Physiology and the Animal Breeding Research Institute, Edinburgh University

1. A number of patients who were being treated with irradiated milk were examined. They showed no change in the Arneth count and the serum-calcium level.

2. Oral administration of colloidal calcium preparation in rabbits gave rise to no increase in the serum-calcium level and had no effect on the count.

3. Intramuscular injections of a colloidal calcium preparation raised the serum-calcium level and produced a regenerative deflection of the count.

4. Intravenous injections of calcium chloride raised the serumcalcium level and produced a regenerative deflection of the count.

5. Intravenous injections of hypotonic solutions produced no demonstrable effect on the serum-calcium level, but caused a regenerative deflection of the count.

6. Intravenous injections of physiological saline solutions produced no effect on the serum-calcium level and had no effect on the count.

I beg to thank Professor F. A. E. CREW for permitting the experimental portion of this investigation to be conducted in his laboratory.

This research was carried out during the tenure of a grant from the Littauer Fund. A portion of the costs was defrayed by a grant from the Earl of Morav Fund.