Experimental Physiology
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Quarterly Journal of Experimental Physiology 21.2 pp 187-192
© The Physiological Society 1931
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THE DIFFUSION OF ORTHOPHOSPHATE INTO AND FROM MUSCLE

Eugenia Semeonoff 1

1 Department of Physiology, Edinburgh University

1. Using the diffusion method described, the concentration of phosphate in a Ringer solution necessary for equilibrium with resting frog muscle is about 20 mgms. per cent., and with fatigued muscle about 50 mgms. per cent.

2. These results are in agreement with those found by direct estimation, therefore all the inorganic phosphate of muscle is freely diffusible.

3. A muscle placed in oxygenated Ringer solution containing phosphate, and then suspended in oxygen, establishes a constant resting equilibrium whatever the concentration of phosphate in the surrounding fluid may be.

4. No isotonic strength of Ringer solution could be found for muscle in rigor.

Submitted on July 8, 1931






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Copyright © 1931 by the The Physiological Society.