Experimental Physiology
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Quarterly Journal of Experimental Physiology 22.1 pp 1-5
© The Physiological Society 1932
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THE RESPONSES OF THE BATRACHIAN ALIMENTARY CANAL TO AUTONOMIC DRUGS. XENOPUS LÆVIS (THE SOUTH AFRICAN CLAWED TOAD)-ARECOLINE

David Epstein 1

1 Department of Pharmacology, University of Cape Town

1. Arecoline causes contraction of every portion of the alimentary canal of Xenopus lævis (the South African clawed toad), and this is antagonised by atropine.

2. These responses have been interpreted as proving that the whole of the digestive tract of X. lævis receives motor (excitatory) fibres from the parasympathetic system.

3. Arecoline, under certain conditions, is a more suitable drug than pilocarpine for demonstrating the presence of parasympathetic motor (excitatory) fibres.

Submitted on January 18, 1932







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Copyright © 1932 by the The Physiological Society.