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Quarterly Journal of Experimental Physiology 24.1 pp 69-75
© The Physiological Society 1934
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INVESTIGATIONS ON THE PHARMACOLOGY OF EVIPAN SODIUM

Walter P. Kennedy 1 and Basudeva Narayana 1

1 The Department of Physiology, Edinburgh University

(1) The depressant action of evipan sodium on the frog heart is very rapidly removed by washing, and is antagonised by adrenalin. Complete recovery can be obtained in a few minutes.

(2) No significant effect is produced by evipan sodium on the blood-sugar of rabbits or guinea-pigs.

(3) Respiration is markedly slowed and temperature reduced by this anæsthetic.

(4) The detoxication of evipan sodium in mammals is very rapid.

The investigation was carried out under a grant from the Carnegie Trust, and Bayer Products kindly supplied the evipan sodium used.

Submitted on July 12, 1933






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Copyright © 1934 by the The Physiological Society.