Experimental Physiology
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Quarterly Journal of Experimental Physiology 24.2 pp 169-175
© The Physiological Society 1934
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MODE OF ACTION OF OXYGEN LACK AND CARBON DIOXIDE EXCESS ON RESPIRATION IN THE RABBIT

Samson Wright 1

1 The Department of Physiology, Middlesex Hospital Medical School

1. The mode of action of oxygen lack and carbon dioxide excess was examined in the rabbit.

2. Oxygen lack (as in the cat) depresses the "deafferented" respiratory centre and produces reflex stimulation through the sinus, aortic, and vagus nerves. The sinus afferents are probably more important than the others. The vagal fibres employed are probably aortic and not pulmonary in origin.

3. Carbon dioxide excess acts predominantly centrally. Afferent impulses in the sinus nerves are of inconstant importance, but no convincing evidence was obtained that the vago-aortic nerves participated in any significant degree in the total response.

Submitted on February 23, 1934






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Copyright © 1934 by the The Physiological Society.