POST-MORTEM GLYCOGENOLYSIS IN RABBIT LIVER

¹ The Department of Physiology, University of Aberdeen

1. The rate of glycogenolysis in excised rabbit liver slices, incubated at 380° C., is not determined by the percentage of glycogen initially present.

2. The lactic acid increases but little, "free sugar" increases markedly, but the two together never suffice to account for the glycogen which disappears.

3. No increase in reducing power follows acid hydrolysis of alcoholic extracts of the liver.

4. The results are similar whether the glycogenolysis occurs in air or in nitrogen.

The author wishes to express his best thanks to Professor J. J. R. Macleod for suggesting the subject and for helpful discussions in the course of the experiments; also to the Medical Research Council for aid from their grant to Professor Macleod and Dr. J. M. Peterson.