Experimental Physiology
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Quarterly Journal of Experimental Physiology 25.1 pp 77-83
© The Physiological Society 1935
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THE EFFECT OF OVARIAN EXTRACTS ON THE OXYGEN CONSUMPTION OF THE UTERUS

M. A. Khayyal 1 and C. M. Scott 1

1 The Department of Pharmacology, University of Edinburgh

1. Fresh follicular fluid from cows ovaries contains a substance which causes an increase in the oxygen consumption rate of the isolated uterus of mice.

2. This substance is neither cestrin nor the luteal hormone, nor was it found in the blood serum of men and women.

3. Evidence is put forward that this metabolic substance is released from the ovary by the action of the hormones of the anterior pituitary gland, but these latter hormones have no direct action on the oxygen consumption of the isolated uterus.

4. Thyroxine causes a rise in the rate of oxygen consumption of the isolated mouse uterus.

5. Male hormone causes no rise in uterine oxygen consumption.

We thank Professor A. J. Clark for his help during this investigation. The expenses were paid by a grant from the Moray Fund of Edinburgh University.

Submitted on December 6, 1934






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Copyright © 1935 by the The Physiological Society.