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Quarterly Journal of Experimental Physiology 26.3 pp 299-303
© The Physiological Society 1937
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EFFECT OF SNAKE VENOMS ON GLYCOLYSIS AND FERMENTATION IN CELL-FREE EXTRACTS

E. Chain 1

1 The Sir William Dunn School of Pathology, Oxford

A number of dried snake venoms contain a substance which inhibits completely glycolysis in a cell-free muscle extract and fermentation in a yeast maceration juice when added to these solutions in concentrations of 0·2 to 2 mg. per c.c. The inhibiting substance of some venoms is not affected by heating the solutions for 10 minutes at 100° C.; in some venoms it is destroyed by this procedure.

Note:

I am greatly indebted to Dr. B. Barnett, Zoological Society, London, to Dr. A. Hughes, Colloid Science Laboratory, Cambridge, and to Prof. Ledingham, Director of the Lister Institute, London, for their kind gifts of samples of snake venoms.

I am indebted to the Christopher Welsh Fund for a grant towards the cost of apparatus.

Submitted on December 21, 1936






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Copyright © 1937 by the The Physiological Society.