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Quarterly Journal of Experimental Physiology and Cognate Medical Sciences 28.1 pp 23-31
© The Physiological Society 1938
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THE EFFECT OF THE ALARM REACTION ON WATER EXCRETION

St. Karády 1, J. S. L. Browne 1, and H. Selye 1

1 McGill University Clinic, Royal Victoria Hospital, and the Department of Anatomy, Histology and Embryology, McGill University, Montreal, Canada

Experiments in the rat have confirmed the conception that an alarm reaction decreases the urine output irrespective of the stimulus which has been used to elicit it.

If during the course of an alarm reaction produced by any stimulus the same or any other stimulus is given, then the second stimulus not only fails to cause water retention but actually increases urine output.

These findings are in good accord with the assumption that two alarm reactions cannot be elicited in rapid succession, and that an alarm reaction produced by one stimulus raises the resistance of the organism both against this stimulus and against any other alarming agent.

Submitted on February 28, 1938






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Copyright © 1938 by the The Physiological Society.