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Quarterly Journal of Experimental Physiology 3.3 pp 289-296
© The Physiological Society 1910
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THE EXCRETION OF CREATIN IN DIABETES

R. A. Krause 1

1 Chemical Laboratory of the Physiology Department, Edinburgh University

1. Typical diabetes mellitus is associated with the excretion of creatin in the urine.

This conclusion is confirmed by the observations of Krause and Cramer on the appearance of creatin in the urine in phloridzin diabetes. It is in agreement with the observations of Cathcart on the creatin excretion of normal persons living on a diet free from carbohydrates.

2. In each of the cases examined the excretion of creatinin was found to be below the normal.

3. Observations are recorded regarding the fallacies which are introduced in the estimation of creatin and creatinin by the presence of small quantities of acetone and its allies.

This work was carried out at the suggestion of Dr Cramer, to whom I desire to express my indebtedness for advice and assistance. I also wish to thank Professor Greenfield, Dr Gibson, and Dr Russell for their kindness in giving me facilities for the study of cases in their wards.

Submitted on August 3, 1910






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