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Quarterly Journal of Experimental Physiology and Cognate Medical Sciences 41.3 pp 290-294
© The Physiological Society 1956
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THE EFFECT OF LOWERED BODY TEMPERATURE ON HISTAMINE-INDUCED GASTRIC SECRETION

J. A. Gillespie 1

1 The University Department of Surgery, Western Infirmary, Glasgow

The effect of lowered body temperature on histamine-induced gastric secretion in the cat has been studied. Both the acidity and the volume of the juice fell rapidly on cooling the animal, a 15° C. reduction in temperature reducing acid secretion by about three-quarters. The free acid content of the juice tended to be reduced to a greater extent than the volume, that is, there is a change in the composition of the juice as the animal's temperature is lowered. On rewarming, secretion recovered, though less rapidly than it fell off during cooling.

Note:

I wish to thank Professor C. F. W. Illingworth for his kindness in allowing me to carry out this work in his department. I have also to thank Miss M. W. Mackenzie for drawing the graphs, and Mr. Stanley Brown for technical assistance.

Submitted on January 25, 1956






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Copyright © 1956 by the The Physiological Society.