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Quarterly Journal of Experimental Physiology and Cognate Medical Sciences 41.3 pp 309-317
© The Physiological Society 1956
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CHANGES IN THE SOLUBILITY OF CHOLESTEROL DURING THE INTERACTION OF CHYLE AND PLASMA

D. S. Robinson 1, P. M. Harris 1, and J. E. French 1

1 The Sir William Dunn School of Pathology, Oxford

1. In the rat, the clearing of chyle by heparinized plasma allows the subsequent clearing of turbid suspensions of cholesterol.

2. This secondary clearing of cholesterol is probably due to solution of the cholesterol in the fatty acid-protein complexes produced during the clearing of chyle.

3. This process is presumably related to the solution of cholesterol suspensions in colloidal soaps, and some observations on this system are presented.

Note:

The authors would like to thank Sir Howard Florey for his advice and interest in this work. They are indebted to Mr. H. W. Wheal for his technical assistance.

A personal grant from the Albert and Mary Lasker Foundation Inc. to Miss P. M. Harris is gratefully acknowledged.

Submitted on March 22, 1956






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Copyright © 1956 by the The Physiological Society.