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Quarterly Journal of Experimental Physiology and Cognate Medical Sciences 55.1 pp 25-35
© The Physiological Society 1970
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NERVOUS TRANSMISSION IN THE SUPERIOR CERVICAL GANGLION OF THE THIAMINE-DEFICIENT RAT

V. Perri 1, O. Sacchi 1, and C. Casella 1

1 Institutes of General Physiology and Human Physiology, University of Pavia, Italy

The amplitude of the post-ganglionic potential was measured in isolated preparations of the superior cervical ganglion from rats at different stages of thiamine deficiency.

At low frequency stimulation (0·5/sec) a decrease in the post-ganglionic potential amplitude was not observed until the final stages of thiamine deficiency. At high frequency stimulation (20/sec) the post-ganglionic potential of the thiamine-deficient rats showed an early and much more pronounced decrease in comparison with that observed in both normal animals and pair-fed controls.

The amplitude and conduction velocity of the different components of the sympathetic cord action potential were unaffected by thiamine deficiency.

Note:

This research was partly supported by a Grant from the Richardson Merrell S.p.A., Naples.

Submitted on March 3, 1969






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Copyright © 1970 by the The Physiological Society.