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Quarterly Journal of Experimental Physiology and Cognate Medical Sciences 56.1 pp 12-17
© The Physiological Society 1971
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EFFECTS OF AGE AND ENVIRONMENTAL TEMPERATURE ON THE JUXTAGLOMERULAR APPARATUS OF HOUSE MICE

S. A. Barnett 1 and R. F. Macadam 2

1 Department of Zoology, University of Glasgow, Scotland
2 Department of Pathology (Western Infirmary), University of Glasgow, Scotland

The kidneys of wild house mice, Mus musculus, L., aged 16, 28 and 100 weeks, were examined histologically, with special reference to the state of the juxtaglomerular apparatus (JGA). Some of the mice were kept in an environment at 21°C, others at -3°C. The percentage of glomeruli with JGAs containing cells with granulated cytoplasm was unaffected by environmental temperature, but declined with age. The decline was not related to the presence of inflammatory lesions or glomerular sclerosis.

Note:

The research was aided by grants to SAB by the Medical Research Council. We are also much indebted to Raymond Stoddart for technical help.

Submitted on April 30, 1970






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Copyright © 1971 by the The Physiological Society.