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Quarterly Journal of Experimental Physiology and Cognate Medical Sciences 56.1 pp 41-45
© The Physiological Society 1971
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THE ONSET OF FUNCTIONAL CAPACITY IN FETAL GUINEA-PIG PARATHYROID GLANDS

R. W. Graham 1 and R. J. Scothorne 1

1 Department of Anatomy, University of Newcastle upon Tyne

Parathyroid tissue or pharyngeal pouch tissue containing the presumptive primordium of parathyroid III from embryonic guinea-pigs has been explanted to the chick chorioallantoic membrane in contact with a piece of neonatal rat parietal bone. Histological study of the conjoined grafts, removed 4-7 days later, showed bone resorption, indicative of parathyroid secretory activity, at developmental ages of 23 days and older.

Note:

The assistance of Messrs D. Auld (histology), J. Brunton Layfield (photomicrography), and D. L. McLean (Animal House Superintendent) is gratefully acknowledged. This study was generously supported by grants from the Medical Research Council and the British Empire Cancer Campaign.

Submitted on May 28, 1970






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Copyright © 1971 by the The Physiological Society.