Experimental Physiology
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Quarterly Journal of Experimental Physiology 68.1 pp 97-104
© The Physiological Society 1983
This Article
Right arrow Full Text (PDF)
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by House, C. R.
Right arrow Articles by Bland, K. P.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by House, C. R.
Right arrow Articles by Bland, K. P.

UPTAKE OF CHLOROTETRACYCLINE INTO MOUSE EGGS

C. R. House 1 and K. P. Bland 1

1 Department of Veterinary Physiology, University of Edinburgh, Summerhall, Edinburgh EH9 1QH

The fluorescent compound chlorotetracycline (CTC) enters the mouse egg by a mechanism. controlled by the oolemma. The intracellular distribution of CTC is non-uniform and during the early stages of uptake fluorescent patches are observed at the egg's surface probably close to the oolemma. Lanthanum blocks the entry of CTC into the egg's cytoplasm and in this condition the CTC remains at the surface of the egg; the labelled site is not the zona pellucida and is likely to be the outer surface of the oolemma. The results of this study of CTC uptake support the idea that this compound labels divalent ( or trivalent) cations in the neighbourhood of cell membranes.

Submitted on May 11, 1982






HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 1983 by the The Physiological Society.