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Quarterly Journal of Experimental Physiology 73.1 pp 143-145
© The Physiological Society 1988
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TEMPERATURE-DEPENDENCE OF A FAST MOTILE RESPONSE IN ISOLATED OUTER HAIR CELLS OF THE GUINEA-PIG COCHLEA

J. F. Ashmore 1 and M. C. Holley 1

1 Department of Physiology, Medical School, University Walk, Bristol BS8 1TD

Isolated outer hair cells (OHC) of the cochlea exhibit a motility which can be driven at acoustic frequencies (Ashmore, 1987). The temperature-dependence of the movement is reported here for the range 20-37 °C. OHC are shown to be motile at 37 °C. The temperature-dependence is quite weak, with Q10 = 1·33. The observation is difficult to reconcile with mechanisms involving an intermediate biochemical messenger, including those based on actomyosin.

Submitted on October 23, 1987
Accepted on October 29, 1987




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J. Ashmore
Cochlear Outer Hair Cell Motility
Physiol Rev, January 1, 2008; 88(1): 173 - 210.
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