Experimental Physiology
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Quarterly Journal of Experimental Physiology 73.3 pp 447-449
© The Physiological Society 1988
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TIME COURSE OF THE CHANGE IN NUCLEAR 3,5,3'-TRIIODOTHYRONINE RECEPTORS OF SKELETAL MUSCLE IN RELATION TO ENERGY INTAKE

R. Geers 1, D. L. Ingram 2, and M. J. Dauncey 2

1 Catholic University, Leuven, Belgium
2 AFRC Institute of Animal Physiology and Genetics Research, Babraham, Cambridge CB2 4AT

Nuclear triiodothyronine receptors have been investigated in skeletal muscle from young pigs living at thermal neutrality (26°). Animals were fed at a high (H) or low (L) level of energy intake for 3 or 21 days and killed at 6 or 24 h after the last meal. Receptor numbers were significantly greater on the H than the L intake, even after only 3 days of treatment. The difference in receptors between animals on H and L diets was somewhat less at 6 compared with 24 h after feeding. It is postulated that these changes could be mediated through the action of glucagon.

Submitted on February 15, 1988
Accepted on February 24, 1988






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Copyright © 1988 by the The Physiological Society.