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MYOSIN LIGHT CHAINS IN REGENERATING RAT SKELETAL MUSCLE FOLLOWING CHRONIC, LOW-FREQUENCY, ELECTRICAL STIMULATION
1 The Physiological Laboratory, Downing Street, Cambridge CB2 3EG
2 Departments of Community Health and Surgery, University of Toronto, Toronto, Ontario M5S 1A8, Canada
3 Department of Kinesiology, University of Waterloo, Waterloo, Ontario N2L 3G1, Canada
4 Department of Surgery, University of Toronto, Toronto, Ontario M5S 1A8, Canada
5 Departments of Community Health, University of Toronto, Toronto, Ontario M5S 1A8, Canada
Ten days of chronic, low-frequency, electrical stimulation of regenerating rat extensor digitorum longus muscle causes an increase in the percentage of slow, phosphorylatable myosin light chains with a complementary decrease in the total fast light chain content. This altered light chain expression is similar to that observed when electrical stimulation is applied to a developing muscle in vivo.
Submitted on March 11, 1988
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