Experimental Physiology
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Quarterly Journal of Experimental Physiology 73.5 pp 797-800
© The Physiological Society 1988
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RECOVERY FROM IMMOBILIZATION-INDUCED ATROPHY OF RABBIT SOLEUS MUSCLES CAN BE ACCELERATED BY CHRONIC LOW-FREQUENCY STIMULATION

Mary Cotter 1, Jacqueline Barry 1, and Norman Cameron 1

1 Department of Physiology, Marischal College, University of Aberdeen, Aberdeen AB9 1AS

Immobilization of rabbit soleus muscles with an ankle joint angle of 90° led to gross degeneration after 2 weeks. Natural recovery in the subsequent 2 weeks had little effect on the mean area of soleus fibres, although there were signs of regeneration. However chronic low-frequency activation of soleus muscles by nerve stimulation greatly accelerated recovery, producing muscle fibres of normal areas and with characteristics of maturity.

Submitted on July 4, 1988
Accepted on July 12, 1988






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Copyright © 1988 by the The Physiological Society.