Experimental Physiology
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Quarterly Journal of Experimental Physiology 73.6 pp 1005-1008
© The Physiological Society 1988
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TISSUE ELECTROLYTES IN THE RABBIT FOLLOWING CHRONIC DIETARY POTASSIUM DEPLETION

Jeremy P. T. Ward 1

1 Department of Medicine, St Thomas's Hospital Medical School, Lambeth Palace Road, London SE1 7EH

Tissue electrolytes were estimated in rabbits following chronic dietary K+ depletion, and after a week of subsequent K+ repletion. The heart, liver and brain all exhibited protection against K+ loss following K+ depletion, whereas skeletal muscle did not. Both Na+ and total magnesium were elevated in quadriceps, but not in other tissues. After 1 week of K+ repletion the heart and liver both showed a significant overshoot in tissue K+, but no change in total magnesium. It is suggested that the liver may have a similar adaptation to depletion as that reported for the heart (Ward & Cameron, 1984).

Submitted on August 8, 1988
Accepted on August 24, 1988






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Copyright © 1988 by the The Physiological Society.