Experimental Physiology
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Quarterly Journal of Experimental Physiology 74.2 pp 207-209
© The Physiological Society 1989
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THE EFFECTS OF PROLONGED EXPOSURE TO LOWERED AMBIENT TEMPERATURE ON THYROID ACTIVITY IN MATURE FEMALE RATS

I. I. Ibidapo 1 and O. A. Sofola 1

1 Department of Physiology, College of Medicine, University of Lagos, P.M.B. 12003, Lagos, Nigeria

The effects of prolonged exposure to lowered ambient temperature (18-19 °C) for 6 weeks, on thyroid function, were studied in mature female rats. Exposure to cold resulted in a significant rise in serum thyrotrophin level but a fall in serum thyroxine. Radioactive iodine uptake by the thyroid gland was also depressed. Rectal temperature was reduced following cold exposure. Histological examination of the thyroid gland was suggestive of reduced glandular activity. Thus prolonged exposure to lowered ambient temperature leads to a reduction in thyroid gland activity which is accompanied by a lower body temperature.

Submitted on November 28, 1988
Accepted on November 30, 1988






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Copyright © 1989 by the The Physiological Society.