Experimental Physiology
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Quarterly Journal of Experimental Physiology 74.6 pp 951-953
© The Physiological Society 1989
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FATIGUE OF ISOLATED MOUSE MUSCLE DUE TO ISOMETRIC TETANI AND TETANI WITH HIGH POWER OUTPUT

Michelle E. Cummins 1, Rabinder S. Soomal 1, and N. A. Curtin 1

1 Department of Physiology, Charing Cross and Westminster Medical School, Fulham Palace Road, London W6 8RF

The fatiguing effect of a series of isometric tetani and of tetani with shortening and maximum power output were compared using soleus and extensor digitorum longus muscle of mouse. Mean force in test isometric tetani after the series was reduced by up to 35 % compared with pre-series controls. Tetani with shortening were always more fatiguing than isometric tetani.

Submitted on August 24, 1989
Accepted on September 19, 1989




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D. G. Allen, G. D. Lamb, and H. Westerblad
Skeletal Muscle Fatigue: Cellular Mechanisms
Physiol Rev, January 1, 2008; 88(1): 287 - 332.
[Abstract] [Full Text] [PDF]




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