Experimental Physiology
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Experimental Physiology 75.2 pp 259-261
© The Physiological Society 1990
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Experimental Physiology, Vol 75, Issue 2, 259-261
Copyright © 1990 by The Physiological Society

Article

Hepatic branch vagotomy attenuates the feeding response to 2-deoxy-D-glucose in rats

E Delprete and E Scharrer

The effect of hepatic branch vagotomy on the feeding response induced in rats by intraperitoneally injected 2-deoxy-D-glucose (2-DG) was tested. Injections were given 1 h after onset of the dark phase, and immediately [corrected] after the rats had ingested a meal. 2-DG produced a smaller feeding response in hepatic branch-vagotomized rats compared with that in sham-vagotomized rats. This finding suggests that hepatic glucoreceptors with vagal afferent fibres are involved in the feeding response to glucose deprivation.


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Copyright © 1990 by the The Physiological Society.