Experimental Physiology
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Experimental Physiology 76.4 pp 623-626
© The Physiological Society 1991
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Experimental Physiology, Vol 76, Issue 4, 623-626
Copyright © 1991 by The Physiological Society


Article

The role of calcitonin gene-related peptide in gastric mucosal protection in the rat

ER Forster and GJ Dockray

The presence of circulating antibodies to calcitonin gene-related peptide (CGRP) enhanced the damaging effect of ethanol on the rat gastric mucosa. Taken together with previous experimental and morphological data the results suggest that CGRP released from the peripheral terminals of visceral afferent fibres plays a role in mediating gastric mucosal defence mechanisms.





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Copyright © 1991 by the The Physiological Society.