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Cells derived from explants of guinea-pig gall-bladder maintained in culture for up to 14 days, exhibit a network of cytoskeletal filaments that are labelled by an anti-cytokeratin antibody, but not by an anti-desmin antibody, suggesting that they are of epithelial origin. These cells proved suitable for patch-clamp studies and by using this method channels selective for K+ and Cl- were observed.
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P. J. Gunter-Smith, O. Abdulkadir, L. Hammonds-Odie, M. Scanlon, and R. Terrell A primary culture of guinea pig gallbladder epithelial cells that is responsive to secretagogues Am J Physiol Gastrointest Liver Physiol, November 1, 2000; 279(5): G866 - G874. [Abstract] [Full Text] [PDF] |
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