Experimental Physiology
	

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Experimental Physiology 77.1 pp 229-232
© The Physiological Society 1992
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Experimental Physiology, Vol 77, Issue 1, 229-232
Copyright © 1992 by The Physiological Society


Article

Electric field-induced orientation of rat hippocampal neurones in vitro

AM Rajnicek, NA Gow, and CD McCaig

Rat hippocampal neurones in primary culture exhibited directional growth in response to DC electric fields. Neurites lay perpendicular to the field after exposure to 28, 80 or 219 mV/mm but there was no orientation effect at 9 mV/mm or in unexposed control cultures. Fields that evoked perpendicular responses also reduced the number of cathode-facing neurites. Orientation was the same for neurite initiation sites and the direction of overall neurite growth.


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J. Cell Sci.Home page
A Rajnicek, S Britland, and C McCaig
Contact guidance of CNS neurites on grooved quartz: influence of groove dimensions, neuronal age and cell type
J. Cell Sci., January 12, 1997; 110(23): 2905 - 2913.
[Abstract] [PDF]




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Copyright © 1992 by the The Physiological Society.