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Development of microvillus structure on the surface of enterocytes migrating over follicle-associated lymphoid tissue appears to take place in an identical way to that seen on villus enterocytes. M-cells, which are not found in crypts, possess microvilli of constant length in all parts of the follicle dome epithelial tissue. The surface area of M-cell microvilli is not however different from that determined on fully formed follicle-associated enterocytes. These results support the hypothesis that M-cell formation takes place throughout the dome epithelium by immune-induced transformation of already existing enterocytes.
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T Kucharzik, N Lugering, K W Schmid, M A Schmidt, R Stoll, and W Domschke Human intestinal M cells exhibit enterocyte-like intermediate filaments Gut, January 1, 1998; 42(1): 54 - 62. [Abstract] [Full Text] [PDF] |
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