Experimental Physiology
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Experimental Physiology 77.4 pp 649-652
© The Physiological Society 1992
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Experimental Physiology, Vol 77, Issue 4, 649-652
Copyright © 1992 by The Physiological Society

Article

Intracellular sodium and potassium activities of skeletal muscle fibres of hypothyroid rats

M MacDermott

In soleus muscle fibres of hypothyroid rats, the membrane potential (Vm) and the intracellular K+ activity (aKi) were significantly lower than in control muscles. These results are consistent with the well-documented decrease in the number of Na(+)-K+ pumps which occurs in hypothyroid muscles. aNai was unchanged in the hypothyroid muscles but this may reflect a change in passive Na+ fluxes which has been reported to occur in association with changes in the number of pump units.




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Copyright © 1992 by the The Physiological Society.