Openings in the endothelium of frog mesenteric microvessels associated with acute inflammation following mild thermal injury have been examined by reconstruction from serial ultrathin sections. While all the openings lay close to the intercellular junctions only a minority (seven out of thirty-eight) were continuous with the intercellular clefts. The majority of gaps or openings (thirty-one out of thirty-eight) were transcellular and passed through the peripheral cytoplasm of one endothelial cell, separated from the intercellular cleft by a cellular process which was usually less than 2 microns wide.

This article has been cited by other articles:

				N. E. Vlahakis and R. D. Hubmayr Cellular Stress Failure in Ventilator-injured Lungs Am. J. Respir. Crit. Care Med., June 15, 2005; 171(12): 1328 - 1342. [Abstract] [Full Text] [PDF]

				O. Gajic, J. Lee, C. H. Doerr, J. C. Berrios, J. L. Myers, and R. D. Hubmayr Ventilator-induced Cell Wounding and Repair in the Intact Lung Am. J. Respir. Crit. Care Med., April 15, 2003; 167(8): 1057 - 1063. [Abstract] [Full Text] [PDF]

				C. C. Michel and F. E. Curry Microvascular Permeability Physiol Rev, July 1, 1999; 79(3): 703 - 761. [Abstract] [Full Text] [PDF]

				U Gotsch, E Borges, R Bosse, E Boggemeyer, M Simon, H Mossmann, and D Vestweber VE-cadherin antibody accelerates neutrophil recruitment in vivo J. Cell Sci., January 3, 1997; 110(5): 583 - 588. [Abstract] [PDF]