Experimental Physiology
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Experimental Physiology 78.6 pp 847-850
© The Physiological Society 1993
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Experimental Physiology, Vol 78, Issue 6, 847-850
Copyright © 1993 by The Physiological Society

Article

Heat stress increases ammonia accumulation during exercise in humans

RJ Snow, MA Febbraio, MF Carey, and M Hargreaves

Seven men were studied during 40 min of exercise at 70% VO2 peak, in an environmental chamber maintained at either 20 or 40 degrees C, to examine the effect of heat stress on ammonia metabolism during exercise. Heart rate and rectal and muscle temperatures were higher during exercise in the heat, while no differences were observed in pulmonary oxygen uptake or respiratory exchange ratio. Plasma ammonia levels and muscle ammonia accumulation were higher during exercise at 40 degrees C compared with 20 degrees C. Such metabolic alterations may be associated with reduced performance during exercise in the heat.


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