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Experimental Physiology 90.2 pp 159-161
DOI: 10.1113/expphysiol.2004.029215
© The Physiological Society 2005
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Symposium Report

Cardiovascular-renal interactions: central and peripheral autonomic control

Dynamic analysis of patterns of renal sympathetic nerve activity: implications for renal function

Gerald F DiBona1

1 Departments of Internal Medicine and Physiology & Biophysics, University of Iowa College of Medicine and, Veterans Administration Medical Center, Iowa City, IA 52242, USA

Abstract

Methods of dynamic analysis are used to provide additional understanding of the renal sympathetic neural control of renal function. The concept of functionally specific subgroups of renal sympathetic nerve fibres conveying information encoded in the frequency domain is presented. Analog pulse modulation and pseudorandom binary sequence stimulation patterns are used for the determination of renal vascular frequency response. Transfer function analysis is used to determine the effects of non-renal vasoconstrictor and vasoconstrictor intensities of renal sympathetic nerve activity on dynamic autoregulation of renal blood flow.

(Received 30 September 2004; accepted after revision 19 November 2004; first published online 16 December 2004)
Corresponding author G. F. DiBona: Department of Internal Medicine, University of Iowa College of Medicine, 200 Hawkins Drive, Iowa City, IA 52242, USA. Email: gerald-dibona{at}uiowa.edu




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