Experimental Physiology Email Content Delivery
HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
QUICK SEARCH:   [advanced]


     

Experimental Physiology 90.3 pp 393-401
DOI: 10.1113/expphysiol.2004.029595
© The Physiological Society 2005
This Article
Right arrow Full Text
Right arrow Full Text (PDF)
Right arrow All Versions of this Article:
90/3/393    most recent
expphysiol.2004.029595v1
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Download to citation manager
Citing Articles
Right arrow Citing Articles via HighWire
Right arrow Citing Articles via Google Scholar
Google Scholar
Right arrow Articles by Ferreira, L. F.
Right arrow Articles by Barstow, T. J.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Ferreira, L. F.
Right arrow Articles by Barstow, T. J.
Related Collections
Right arrow Human, Environmental & Exercise

Dynamics of skeletal muscle oxygenation during sequential bouts of moderate exercise

Leonardo F. Ferreira1, Barbara J. Lutjemeier1, Dana K. Townsend1 and Thomas J. Barstow1

1 Departments of Kinesiology and Anatomy and Physiology, Kansas State University, 66506-0302, Manhattan, KS, USA

In rat muscle, faster dynamics of microvascular PO2 (approximately blood flow{eph_122_mu1}to O2 uptake{eph_122_mu2}ratio) after prior contractions that did not alter blood [lactate] have been considered to be a consequence of faster{eph_122_mu3}kinetics. However, in humans, prior exercise below the lactate threshold does not affect the pulmonary{eph_122_mu4}kinetics. To clarify this apparent discrepancy, we examined the effects of prior moderate exercise on the kinetics of muscle oxygenation (deoxyhaemoglobin, [HHb]{alpha}{eph_122_mu5}) and pulmonary{eph_122_mu6}in humans. Eight subjects performed two bouts (6 min each) of moderate-intensity cycling separated by 6 min of baseline pedalling. Muscle (vastus lateralis) oxygenation was evaluated by near-infrared spectroscopy and{eph_122_mu7}was measured breath-by-breath. The time constant ({tau}) of the primary component of{eph_122_mu8}was not significantly affected by prior exercise (21.5 ± 9.2 versus 25.6 ± 9.7 s; Bout 1 versus 2, P= 0.49). The time delay (TD) of [HHb] decreased (11.6 ± 2.6 versus 7.7 ± 1.5 s; Bout 1 versus 2, P < 0.05) and {tau}[HHb] increased (7.0 ± 3.5 versus 10.2 ± 4.6 s; Bout 1 versus 2, P < 0.05), while the mean response time (TD +{tau}) did not change (18.6 ± 2.7 versus 17.9 ± 3.9 s) after prior moderate exercise. Thus, prior moderate exercise resulted in shorter onset and slower rate of increase in [HHb] during subsequent exercise. These data suggest that prior exercise altered the dynamic interaction between{eph_122_mu9}and{eph_122_mu10}following the onset of exercise.

(Received 3 December 2004; accepted after revision 26 January 2005; first published online 11 February 2005)
Corresponding author T. J. Barstow: Department of Kinesiology, 1A Natatorium, Kansas State University, Manhattan, KS, 66506-0302, USA. Email: tbarsto{at}ksu.edu




This article has been cited by other articles:


Home page
 Am. J. Physiol. Cell Physiol.Home page
B. Glancy, T. Barstow, and W. T. Willis
Linear relation between time constant of oxygen uptake kinetics, total creatine, and mitochondrial content in vitro
Am J Physiol Cell Physiol, January 1, 2008; 294(1): C79 - C87.
[Abstract] [Full Text] [PDF]

Home page
 Diabetes CareHome page
T. A. Bauer, J. E.B. Reusch, M. Levi, and J. G. Regensteiner
Skeletal Muscle Deoxygenation After the Onset of Moderate Exercise Suggests Slowed Microvascular Blood Flow Kinetics in Type 2 Diabetes
Diabetes Care, November 1, 2007; 30(11): 2880 - 2885.
[Abstract] [Full Text] [PDF]

Home page
 Exp PhysiolHome page
A. J. Harper, L. F. Ferreira, B. J. Lutjemeier, D. K. Townsend, and T. J. Barstow
Human femoral artery and estimated muscle capillary blood flow kinetics following the onset of exercise
Exp Physiol, July 1, 2006; 91(4): 661 - 671.
[Abstract] [Full Text] [PDF]

Home page
 J. Appl. Physiol.Home page
S. L. Davis, P. J. Fadel, J. Cui, G. D. Thomas, and C. G. Crandall
Skin blood flow influences near-infrared spectroscopy-derived measurements of tissue oxygenation during heat stress
J Appl Physiol, January 1, 2006; 100(1): 221 - 224.
[Abstract] [Full Text] [PDF]


HOME HELP FEEDBACK SUBSCRIPTIONS ARCHIVE SEARCH TABLE OF CONTENTS
Copyright © 2005 by the The Physiological Society.